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A pyramid diagram categorizing four biological risk groups. Group 1 includes agents like E. coli K-12 and is not associated with disease in healthy adults. Group 2 includes agents like Adenovirus and causes disease that is rarely serious and often treatable. Group 3 includes agents like B. anthracis and causes serious or lethal disease where treatment may be available. Group 4 includes agents like Ebola virus and causes serious or lethal disease with no available treatment and potential aerosol transmission

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