Environmental Health & Safety


Carcinogen Safety and Use Registration

CGHS_Carcinogen_labelarcinogens are chemicals that cause cancer or tumor development, typically after repeated or chronic exposure. Carcinogens are classified by several organizations. The International Agency for Research on Cancer (IARC) is the most respected voice internationally on the classification of cancer causing substances. In the United States, the National Toxicology Program is the organization considered most trusted source in this country on cancer. The most current NTP report on carcinogens can be found online at the National Toxicology Program website.


  1. Step 1: Determine if you have regulated carcinogens

    Each of these chemicals are considered "regulated carcinogens" under the California Code of Regulations, Title 8, Section 5203. For any carcinogen flagged as "Listed", please see guidance in the "Listed Carcinogens" tab.

    1,2 dibromo-3-chloropropane (DBCP) (CAS 96-12-8) 
    1,3-butadiene (CAS 106-99-0)
    2-acetylaminofluorene (CAS 53-96-3) [Listed]
    3,3'-dichlorobenzidine (and its salts) (CAS 91-94-1) [Listed] 
    4,4-methylenebis (2-Chloroaniline) (CAS 101-14-4) 
     (CAS 92-67-1) [Listed] 
    4-dimethylaminoazobenzene (CAS 60-11-7) [Listed] 
    4-nitrobiphenyl (CAS 92-93-3) [Listed]  
    acrylonitrile (CAS 107-13-1) 
    alpha-naphthylamine (CAS 134-32-7) [Listed] 
    arsenic (elemental metal or any inorganic compound except arsine)
    asbestos (CAS 1332-21-4) 
    benzene (CAS 71-43-2) 
    benzidine (and its salts) (CAS 92-87-5) [Listed] 
    beta-naphthylamine (CAS 91-59-8) [Listed] 
    beta-propiolactone (CAS 57-57-8) [Listed] 
    bis-chloromethyl ether (CAS 542-88-1) [Listed] 
    cadmium (all forms and compounds)
    chromium (VI) (all forms and compounds)
    coke oven emissions 
    ethylene dibromide (EDB) (CAS 106-93-4) 
    ethylene oxide (CAS 75-21-8) 
    ethyleneimine (CAS 151-56-4) [Listed] 
    formaldehyde (CAS 50-00-0) 
    lead (and its inorganic or organic acid salts) (CAS 7439-92-1)
    methyl chloromethyl ether (CAS 107-30-2) [Listed] 
    methylene chloride (DCM) (CAS 75-09-2)
    methylenedianiline  (CAS 101-77-9)
    N-nitrosodimethylamine (CAS 62-75-9) [Listed] 
    non asbestiform tremolite, anthophyllite, and actinolite 
    vinyl chloride (CAS 75-01-4)  

    Additionally, you can review the following list of resources to determine if your chemical is considered a carcinogen:

    Regulated Carcinogens Cal/OSHA (8 CCR 5200-5220) 
    Report on Carcinogens National Toxicology Program 
    List of Classifications IARC Monographs (by alphabetical order, CAS, Group, or cancer site)

  2. Step 2: Notify EH&S

    Complete the form before using carcinogens (at least 15 days prior to):

    Carcinogen Use Notification
    Regulated Carcinogens

    What happens after I submit the form? You will receive an email confirmation with the information you entered. EH&S will review the information to determine if additional exposure monitoring is necessary. If applicable, EH&S will contact you to schedule an Exposure Monitoring Assessment. Additionally, the results of the survey will be used by EH&S to comply with the Report of Use requirement for the campus, which must be submitted within 15 days prior to your first use. This report will be submitted to you for posting.

  3. Step 3: Complete an Exposure Monitoring Assessment

    EH&S schedule a session to observe your use of carcinogen(s) to determine if your use exceeds Permissible Exposure Limits (PEL / STEL). This include Air Monitoring and Medical Evaluation.

  4. Step 4: Implement controls

    1. Update your Chemical Inventory
    2. Complete Training in Carcinogen Safety, and other courses based on a training Needs Assessment.
    3. Create Standard Operating Procedure for safe use of regulated carcinogens.
    4. Provide Personal Protective Equipment (PPE).
    5. Identify a designated area for using the carcinogen(s), by posting Signs and Labels to communicate the hazard(s).
    6. Post written reports (Report of Use, Emergency Report, and/or Temporary Worksite Notification) in the location where the regulated carcinogen is in use or other appropriate location where the posting is conspicuous to affected employees.  
  5. Step 5: Notify EH&S prior to first use

    Contact EHS at ehslaboratory@ucr.edu prior to first using the carcinogen(s).

Listed Carcinogens are a small group of regulated chemicals used in research laboratories.  Environmental Health and Safety (EH&S) has developed this UCR Listed Carcinogens Program in order to further facilitate research by providing guidelines that would assist in safety and compliance with applicable federal and state regulations.  This program covers all facilities on campus that handle or store Listed Carcinogens.  The flow chart below highlight the important elements necessary for the safe and legal used of Listed Carcinogens on campus.


For more information, contact EH&S at (951) 827-5528 or email us.

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